FGF19 Protéine
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- Antigène Voir toutes FGF19 Protéines
- FGF19 (Fibroblast Growth Factor 19 (FGF19))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificité
- Optimal preservation of protein structure, post-translational modifications and functions.
- Attributs du produit
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- Recombinant human FGF19 protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Pureté
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- niveau d'endotoxine
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by a cell proliferation assay using balb/c 3T3 cells. The expected ED50 for this effect is 100-150 ng/ml.
- Top Product
- Discover our top product FGF19 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Conseil sur la manipulation
- Resuspend the protein in the desired concentration in proper buffer
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- FGF19 (Fibroblast Growth Factor 19 (FGF19))
- Autre désignation
- Fgf19 (FGF19 Produits)
- Synonymes
- FGF-19 Protein, Fgf15 Protein, fibroblast growth factor 19 Protein, FGF19 Protein, Fgf19 Protein, fgf19 Protein
- Sujet
- The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This growth factor is a high affinity, heparin dependent ligand for FGFR4. Expression of this gene was detected only in fetal but not adult brain tissue. Synergistic interaction of the chick homolog and Wnt-8c has been shown to be required for initiation of inner ear development.
- Poids moléculaire
- 21.8 kDa
- NCBI Accession
- NP_005108
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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