GLI1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2721923

Détail du produit

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GLI1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human GLI1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Autre désignation: Gli1 (GLI1 Produits)

Synonymes: GLI Protein, Gli Protein, Gli-1 Protein, gli1.1 Protein, AV235269 Protein, Zfp-5 Protein, Zfp5 Protein, GLI family zinc finger 1 Protein, GLI family zinc finger 1 S homeolog Protein, GLI-Kruppel family member GLI1 Protein, GLI1 Protein, Gli1 Protein, gli1.S Protein, gli1 Protein

Sujet: This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 117.7 kDa

NCBI Accession: NP_005260

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis