CCL3L1 Protéine

N° du produit ABIN2724561

Détail du produit

Antigène: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Application: Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)

Specificité: Optimal preservation of protein structure, post-translational modifications and functions.

Attributs du produit:

• Recombinant human LD78 beta / CCL3L1 protein expressed in E. coli.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0 ng/ml.

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Conseil sur la manipulation: Resuspend the protein in the desired concentration in proper buffer

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Autre désignation: Ld78 Beta,ccl3l1 (CCL3L1 Produits)

Synonymes: 464.2 Protein, D17S1718 Protein, G0S19-2 Protein, LD78 Protein, LD78BETA Protein, MIP1AP Protein, SCYA3L Protein, SCYA3L1 Protein, C-C motif chemokine ligand 3 like 1 Protein, chemokine (C-C motif) ligand 3-like 1 Protein, CCL3L1 Protein

Sujet: This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility.[provided by RefSeq, Apr 2014]

Poids moléculaire: 7.7 kDa

NCBI Accession: NP_001001437

Pathways: Cellular Response to Molecule of Bacterial Origin