MAX Protein (Transcript Variant 1) (His tag)

N° du produit ABIN2725572

Détail du produit

Antigène: MAX (MYC Associated Factor X (MAX))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette MAX protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MAX (transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 95 % as determined by SDS-PAGE and Coomassie blue staining

niveau d'endotoxine: < 0.1 EU per μg protein as determined by LAL test

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 50 mM Imidazole, 250 mM NaCl, pH 8.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MAX (MYC Associated Factor X (MAX))

Autre désignation: Max (MAX Produits)

Synonymes: CG9648 Protein, Dmel\\CG9648 Protein, MAX Protein, bHLHd9 Protein, dMax Protein, dmax Protein, max Protein, bhlhd4 Protein, bhlhd5 Protein, bhlhd6 Protein, bhlhd7 Protein, bhlhd8 Protein, xmax2 Protein, xmax4 Protein, xmax Protein, AA960152 Protein, AI875693 Protein, bHLHd4 Protein, bHLHd5 Protein, bHLHd6 Protein, bHLHd7 Protein, bHLHd8 Protein, fa92b04 Protein, fb52a04 Protein, fb95h11 Protein, wu:fa92b04 Protein, wu:fb52a04 Protein, wu:fb95h11 Protein, zmax Protein, CG9648 gene product from transcript CG9648-RD Protein, MYC associated factor X L homeolog Protein, MYC associated factor X Protein, Max protein Protein, MYC associated factor X S homeolog Protein, myc associated factor X Protein, Max Protein, max.L Protein, MAX Protein, max Protein, max.S Protein

Sujet: The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 18.3 kDa

NCBI Accession: NP_002373

Pathways: Mitotic G1-G1/S Phases