MAX Protein (GST tag,His tag)

N° du produit ABIN7317333

Détail du produit

Antigène: MAX (MYC Associated Factor X (MAX))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette MAX protéine est marqué à la GST tag,His tag.

Fonction: Recombinant Human MAX Protein (His &GST Tag)

Séquence: Met 1-Ser160

Attributs du produit: A DNA sequence encoding the human MAX (NP_002373) (Met1-Ser160) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.

Pureté: > 85 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: MAX (MYC Associated Factor X (MAX))

Autre désignation: MAX (MAX Produits)

Synonymes: CG9648 Protein, Dmel\\CG9648 Protein, MAX Protein, bHLHd9 Protein, dMax Protein, dmax Protein, max Protein, bhlhd4 Protein, bhlhd5 Protein, bhlhd6 Protein, bhlhd7 Protein, bhlhd8 Protein, xmax2 Protein, xmax4 Protein, xmax Protein, AA960152 Protein, AI875693 Protein, bHLHd4 Protein, bHLHd5 Protein, bHLHd6 Protein, bHLHd7 Protein, bHLHd8 Protein, fa92b04 Protein, fb52a04 Protein, fb95h11 Protein, wu:fa92b04 Protein, wu:fb52a04 Protein, wu:fb95h11 Protein, zmax Protein, CG9648 gene product from transcript CG9648-RD Protein, MYC associated factor X L homeolog Protein, MYC associated factor X Protein, Max protein Protein, MYC associated factor X S homeolog Protein, myc associated factor X Protein, Max Protein, max.L Protein, MAX Protein, max Protein, max.S Protein

Sujet:

Background: MYC associated factor X contains 1 basic helix-loop-helix (bHLH) domain and belongs to MAX family. It is highly expressed in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle. MYC associated factor X can form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. MYC associated factor X may also repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Multiple alternatively spliced transcript variants have been described for MYC associated factor X gene but the full-length nature for some of them is unknown.

Synonym: Protein Max, Class D Basic Helix-Loop-Helix Protein 4, bHLHd4, Myc-Associated Factor X, MAX, BHLHD4

Poids moléculaire: 46.1 kDa

NCBI Accession: NP_002373

Pathways: Mitotic G1-G1/S Phases