MCM3 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2725631

Détail du produit

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MCM3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MCM3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Autre désignation: Mcm3 (MCM3 Produits)

Synonymes: HCC5 Protein, P1-MCM3 Protein, P1.h Protein, RLFB Protein, AL033361 Protein, C80350 Protein, Mcmd Protein, P1 Protein, p1.m Protein, cb32 Protein, chunp6867 Protein, wu:fa26g03 Protein, CG4206 Protein, DmMCM3 Protein, DmMcm3 Protein, DmeMCM3 Protein, Dmel\\CG4206 Protein, MCM3 Protein, McM3 Protein, Mcp-PCR2 Protein, PCR2 Protein, dMCM3 Protein, xmcm3 Protein, minichromosome maintenance complex component 3 Protein, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) Protein, Minichromosome maintenance 3 Protein, minichromosome maintenance complex component 3 L homeolog Protein, MCM complex subunit Mcm3 Protein, MCM3 Protein, mcm3 Protein, Mcm3 Protein, mcm3.L Protein

Sujet: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 90.8 kDa

NCBI Accession: NP_002379

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA