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CCL18 Protéine

CCL18 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining Func, AbP, STD, PI Active
N° du produit ABIN2726055
  • Antigène Voir toutes CCL18 Protéines
    CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 12
    • 1
    Humain
    Source
    • 7
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
    Specificité
    Optimal preservation of protein structure, post-translational modifications and functions.
    Attributs du produit
    • Recombinant human MIP4 / CCL18 protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Pureté
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    niveau d'endotoxine
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Assay #1: Determined by its ability to chemoattract human T lymphocytes using a concentration of 1.0-10.0 ng/ml. Assay #2: Determined by its ability to chemoattract human iDCs using a concentration of 1.0-10.0 ng/ml.
    Top Product
    Discover our top product CCL18 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Restrictions
    For Research Use only
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Conseil sur la manipulation
    Resuspend the protein in the desired concentration in proper buffer
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
    Autre désignation
    Mip4,ccl18 (CCL18 Produits)
    Synonymes
    H7AP1 Protein, PARC Protein, RP3-330M21.2 Protein, AMAC-1 Protein, AMAC1 Protein, CKb7 Protein, DC-CK1 Protein, DCCK1 Protein, MIP-4 Protein, SCYA18 Protein, cullin 9 Protein, C-C motif chemokine ligand 18 Protein, CUL9 Protein, CCL18 Protein
    Sujet
    This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.
    Poids moléculaire
    7.8 kDa
    NCBI Accession
    NP_002979
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