RAB8A Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2730373

Détail du produit

Antigène: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RAB8A protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human RAB8A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Autre désignation: Rab8a (RAB8A Produits)

Synonymes: rab8A Protein, DDBDRAFT_0206521 Protein, DDBDRAFT_0214885 Protein, DDB_0206521 Protein, DDB_0214885 Protein, HSH2D Protein, mel Protein, rab8 Protein, c-mel Protein, MEL Protein, RAB8 Protein, zgc:162699 Protein, AA409338 Protein, Mel Protein, Rab8 Protein, rab8A protein Protein, Rab GTPase Protein, RAB8A, member RAS oncogene family Protein, RAB8A, member RAS oncogene family S homeolog Protein, rab8A Protein, RAB8A Protein, rab8a Protein, rab8a.S Protein, Rab8a Protein

Sujet: The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. This protein shares 97 % , 96 %, and 51 % similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4 GTP/GDP-binding sites that are present in all the RAS proteins. The putative effector-binding site of this protein is similar to that of the RAB/YPT proteins. However, this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins. Although this gene was isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrable. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.

Poids moléculaire: 23.5 kDa

NCBI Accession: NP_005361

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome