RGS14 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes RGS14 Protéines
- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette RGS14 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human RGS14 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RGS14 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
- Autre désignation
- Rgs14 (RGS14 Produits)
- Synonymes
- RPIP1 Protein, MGC80558 Protein, RGS14 Protein, rgs14 Protein, wu:fi04g12 Protein, regulator of G protein signaling 14 Protein, regulator of G-protein signaling 14 Protein, regulator of G-protein signaling 14 L homeolog Protein, regulator of G-protein signalling 14 Protein, regulator of G protein signaling 14a Protein, RGS14 Protein, Rgs14 Protein, rgs14.L Protein, rgs14 Protein, rgs14a Protein
- Sujet
- This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
- Poids moléculaire
- 61.3 kDa
- NCBI Accession
- NP_006471
- Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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