TRAF1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2734111

Détail du produit

Antigène: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TRAF1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TRAF1 / EBI6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Autre désignation: Traf1,ebi6 (TRAF1 Produits)

Synonymes: CG3048 Protein, DTRAF Protein, DTRAF1 Protein, Dmel\\CG3048 Protein, TRAF Protein, TRAF1 Protein, Traf1 Protein, dTRAF Protein, dTRAF1 Protein, dTraf1 Protein, dtraf1 Protein, traf1 Protein, traf4 Protein, DKFZp469G032 Protein, EBI6 Protein, MGC:10353 Protein, 4732496E14Rik Protein, TNF receptor associated factor 1 Protein, TNF-receptor-associated factor 4 Protein, TNF receptor-associated factor 1 Protein, TRAF1 Protein, Traf4 Protein, Traf1 Protein, traf1 Protein

Sujet: The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Three transcript variants encoding two different isoforms have been found for this gene.

Poids moléculaire: 46 kDa

NCBI Accession: NP_005649

Pathways: Signalisation NF-kappaB, Apoptose, Cell-Cell Junction Organization, Asymmetric Protein Localization