RYK Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2734730

Détail du produit

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RYK protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Tyrosine-protein kinase RYK (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Autre désignation: Tyrosine-Protein Kinase Ryk (RYK Produits)

Synonymes: RYK Protein, jtk5 Protein, ryk1 Protein, jtk5a Protein, d3s3195 Protein, wu:fb37b12 Protein, wu:fi05b06 Protein, zgc:158381 Protein, MGC114645 Protein, D3S3195 Protein, JTK5 Protein, JTK5A Protein, RYK1 Protein, AW536699 Protein, ERK-3 Protein, Vik Protein, receptor-like tyrosine kinase Protein, receptor-like tyrosine kinase S homeolog Protein, tyrosine-protein kinase RYK Protein, RYK Protein, ryk Protein, ryk.S Protein, LOC100541106 Protein, Ryk Protein

Sujet: The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Poids moléculaire: 67.9 kDa

NCBI Accession: NP_001005861

Pathways: Signalisation RTK, Signalisation WNT, Regulation of Cell Size