VPS4A Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2735431

Détail du produit

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette VPS4A protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human VPS4A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Autre désignation: Vps4a (VPS4A Produits)

Synonymes: vsp4 Protein, SKD1 Protein, SKD1A Protein, SKD2 Protein, VPS4 Protein, VPS4-1 Protein, zgc:153907 Protein, 4930589C15Rik Protein, AI325971 Protein, AW553189 Protein, vacuolar protein sorting 4 homolog A Protein, vacuolar sorting protein 4 Protein, vacuolar protein sorting 4 homolog A L homeolog Protein, vacuolar protein sorting 4a homolog A (S. cerevisiae) Protein, vacuolar protein sorting 4A Protein, VPS4A Protein, TP03_0351 Protein, vps4a Protein, vps4a.L Protein, Vps4a Protein

Sujet: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16 the gene for the other resides on chromosome 18.

Poids moléculaire: 48.7 kDa

NCBI Accession: NP_037377

Pathways: Dynamique des Microtubules, CXCR4-mediated Signaling Events