VPS4A Protein (His tag)

N° du produit ABIN7491269

Détail du produit

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette VPS4A protéine est marqué à la His tag.

Fonction: Recombinant Human VPS4 Protein with C-terminal 6xHis tag

Specificité: VPS4 (Met1-Ser437) 6xHis tag

Attributs du produit: Extracellular Domain Protein

Pureté: The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Autre désignation: VPS4 (VPS4A Produits)

Synonymes: vsp4 Protein, SKD1 Protein, SKD1A Protein, SKD2 Protein, VPS4 Protein, VPS4-1 Protein, zgc:153907 Protein, 4930589C15Rik Protein, AI325971 Protein, AW553189 Protein, vacuolar protein sorting 4 homolog A Protein, vacuolar sorting protein 4 Protein, vacuolar protein sorting 4 homolog A L homeolog Protein, vacuolar protein sorting 4a homolog A (S. cerevisiae) Protein, vacuolar protein sorting 4A Protein, VPS4A Protein, TP03_0351 Protein, vps4a Protein, vps4a.L Protein, Vps4a Protein

Sujet: CIMDAG, SKD1, SKD1A, SKD2, VPS4A, VPS4-1
Description: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18. [provided by RefSeq, Jul 2008]

Poids moléculaire: predicted molecular mass of 49.7 kDa after removal of the signal peptide. The apparent molecular mass of VPS4-His is 55-70 kDa due to glycosylation.

UniProt: Q9UN37

Pathways: Dynamique des Microtubules, CXCR4-mediated Signaling Events