CD58 Protein (CD58) (partial) (Fc Tag)

N° du produit ABIN5608438

Détail du produit

Antigène: CD58

Type de proteíne: Recombinant

Activité biologique: Active

Attributs du protein: partial

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD58 protéine est marqué à la Fc Tag.

Application: Western Blotting (WB), ELISA

Séquence: Phe 29 - Arg 215

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Endotoxin level is less than 1.0 EU per ug by the LAL method.

Biological Activity Comment:

Measured by its binding ability in a functional ELISA. Immobilized Human CD2, His Tag at 2 μg/mL (100 uL/well) can bind Human CD58, Fc Tag with a linear range of 10-156 ng/mL (QC tested).

Information d'application

Indications d'application: This recombinant protein can be used for E, WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 50 mM Tris, 100 mM Glycine, pH 7.5

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C,-80 °C

Stockage commentaire: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.

Détail du antigène

Antigène: CD58

Autre désignation: CD58 (CD58 Produits)

Synonymes: LFA-3 Protein, LFA3 Protein, ag3 Protein, CD58 molecule Protein, CD58 Protein

Sujet: CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

Poids moléculaire: 48.1 kDa

ID gène: 965

UniProt: Q9BRW0