IFNAR2 Protein (AA 27-243) (His-SUMO Tag)

N° du produit ABIN5709721

Détail du produit

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Type de proteíne: Recombinant

Attributs du protein: AA 27-243

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette IFNAR2 protéine est marqué à la His-SUMO Tag.

Application: SDS-PAGE (SDS)

Séquence: ISYDSPDYTD ESCTFKISLR NFRSILSWEL KNHSIVPTHY TLLYTIMSKP EDLKVVKNCA NTTRSFCDLT DEWRSTHEAY VTVLEGFSGN TTLFSCSHNF WLAIDMSFEP PEFEIVGFTN HINVMVKFPS IVEEELQFDL SLVIEEQSEG IVKKHKPEIK GNMSGNFTYI IDKLIPNTNY CVSVYLEHSD EQAVIKSPLK CTLLPPGQES ESAESAK

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Autre désignation: INAR2 (IFNAR2 Produits)

Synonymes: AI747302 Protein, Ifnar-2 Protein, IFN-R Protein, IFN-alpha-REC Protein, IFNABR Protein, IFNARB Protein, IFN-R-2 Protein, IFNBR Protein, interferon alpha and beta receptor subunit 2 Protein, interferon (alpha and beta) receptor 2 Protein, IFNAR2 Protein, Ifnar2 Protein

Sujet: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 3 is a potent inhibitor of type I IFN receptor activity.

Poids moléculaire: 40.74 kDa

UniProt: P48551

Pathways: Signalistation JAK/STAT, Hepatitis C