MBL2 Protein (AA 26-248, partial) (His tag)

N° du produit ABIN5713634

Détail du produit

Antigène: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Type de proteíne: Recombinant

Attributs du protein: AA 26-248, partial

Origine: Boeuf (Vache)

Source: Levure

Purification/Conjugué: Cette MBL2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: NCENIRKTCP VIACGPPGIN GIPGKDGRDG AKGEKGEPGQ GLRGSQGPPG KMGPQGTPGI PGIPGPIGQK GDPGENMGDY IRLATSERAT LQSELNQIKN WLIFSLGKRV GKKAFFTNGK KMPFNEVKTL CAQFQGRVAT PMNAEENRAL KDLVTEEAFL GITDQETEGK FVDLTGKGVT YQNWNDGEPN NASPGEHCVT LLSDGTWNDI ACSASFLTVC EFS

Purification: SDS-PAGE

Pureté: > 90 %

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Stock: -80 °C,4 °C,-20 °C

Stockage commentaire: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Détail du antigène

Antigène: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Autre désignation: MBL2 (MBL2 Produits)

Synonymes: COLEC1 Protein, HSMBPC Protein, MBL Protein, MBL2D Protein, MBP Protein, MBP-C Protein, MBP1 Protein, MBPD Protein, pMBP-27 Protein, mbl2 Protein, MBL1 Protein, cMBl Protein, collectin Protein, Ab2-001 Protein, Ab2-011 Protein, L-MBP Protein, MBL-C Protein, COLEC2 Protein, mbl Protein, etID42583.2 Protein, fb68b07 Protein, hbl3 Protein, wu:fb68b07 Protein, zgc:109836 Protein, mannose binding lectin 2 Protein, Mannose-binding protein C Protein, mannose-binding lectin (protein C) 2, soluble Protein, mannose-binding lectin (protein C) 2 Protein, mannose-binding lectin family member 3, pseudogene Protein, MBL2 Protein, mbl2 Protein, Mbl2 Protein, MBL3P Protein

Sujet: Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complent pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages .

Poids moléculaire: 25.7 kDa

UniProt: O02659

Pathways: Système du Complément, Positive Regulation of Immune Effector Process