CLEC7A Protein (AA 71-244) (His tag)

N° du produit ABIN5854489

Détail du produit

Antigène: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Type de proteíne: Recombinant

Attributs du protein: AA 71-244

Origine: Souris

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette CLEC7A protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: ADPRHNSGRN PEEKDNFLSR NKENHKPTES SLDEKVAPSK ASQTTGGFSQ SCLPNWIMHG KSCYLFSFSG NSWYGSKRHC SQLGAHLLKI DNSKEFEFIE SQTSSHRINA FWIGLSRNQS EGPWFWEDGS AFFPNSFQVR NTVPQESLLH NCVWIHGSEV YNQICNTSSY SICEKELHHH HHH

Pureté: > 95 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Autre désignation: C-type lectin domain family 7 member A 1 (CLEC7A Produits)

Synonymes: CLEC7A Protein, BGR Protein, Clecsf12 Protein, beta-GR Protein, CANDF4 Protein, CLECSF12 Protein, DECTIN1 Protein, Clec7b Protein, RGD1565140 Protein, C-type lectin domain containing 7A Protein, C-type lectin domain family 7, member a Protein, CLEC7A Protein, Clec7a Protein

Sujet: CLEC7A, also known as C-type lectin domain family 7 member A 1, that functions as in the innate immune response to fungal pathogens. It is expressed on monocytes, macrophages, and neutrophils, and on some populations of dendritic cells and T cells. It is upregulated on macrophages by GM-CSF, IL-4, or IL-13 and downregulated by dexamethasone, IL-10, or LPS. Recombinant mouse CLEC7A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 21.0kDa (183aa) 18-28KDa (SDS-PAGE under reducing conditions.)

NCBI Accession: NP_064392

Pathways: Activation of Innate immune Response