CRLF2 Protein (AA 23-231) (His tag)
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- Antigène Voir toutes CRLF2 Protéines
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 23-231
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Origine
- Humain
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Source
- Baculovirus infected Insect Cells
- Purification/Conjugué
- Cette CRLF2 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Séquence
- ADPQGGAAEG VQIQIIYFNL ETVQVTWNAS KYSRTNLTFH YRFNGDEAYD QCTNYLLQEG HTSGCLLDAE QRDDILYFSI RNGTHPVFTA SRWMVYYLKP SSPKHVRFSW HQDAVTVTCS DLSYGDLLYE VQYRSPFDTE WQSKQENTCN VTIEGLDAEK CYSFWVRVKA MEDVYGPDTY PSDWSEVTCW QRGEIRDACA ETPTPPKPKL SKHHHHHH
- Pureté
- > 95 % by SDS - PAGE
- niveau d'endotoxine
- < 1.0 EU per 1 microgram of protein (determined by LAL method)
- Top Product
- Discover our top product CRLF2 Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Antigène
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Autre désignation
- CRLF2 (CRLF2 Produits)
- Synonymes
- CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein
- Sujet
- CRLF2, also known as cytokine receptor-like factor 2 isoform 1, is a receptor for thymic stromal lymphopoietin. It is proposed to signal through a heterodimeric receptor complex that consists of a new member of the hemopoietin family termed CRLF2 and the IL-7R alpha-chain. The protein induces phosphorylation of Stat3 and Stat5 also activate JAK2 pathways. CRLF2 and IL-7R alpha are principally coexpressed on monocytes and dendritic cell populations and to a much lesser extent of various lymphoid cells. Recombinant human CRLF2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
- Poids moléculaire
- 25.2kDa (218aa) 28-40KDa (SDS-PAGE under reducing conditions.)
- NCBI Accession
- NP_071431
- UniProt
- Q9HC73
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