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Glypican 3 Protein (GPC3) (AA 25-559) (His tag)
GPC3
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
N° du produit ABIN5854889
Détail du produit
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Antigène
Voir toutes Glypican 3 (GPC3) Protéines
Glypican 3 (GPC3)
Type de proteíne
Recombinant
Attributs du protein
AA 25-559
Origine
Toutes les origines à travers Glypican 3 Protéines
Humain
Source
Toutes les sources à travers Glypican 3 Protéines
Baculovirus infected Insect Cells
Purification/Conjugué
Cette Glypican 3 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
ADPQPPPPPP DATCHQVRSF FQRLQPGLKW VPETPVPGSD LQVCLPKGPT CCSRKMEEKY QLTARLNMEQ LLQSASMELK FLIIQNAAVF QEAFEIVVRH AKNYTNAMFK NNYPSLTPQA FEFVGEFFTD VSLYILGSDI NVDDMVNELF DSLFPVIYTQ LMNPGLPDSA LDINECLRGA RRDLKVFGNF PKLIMTQVSK SLQVTRIFLQ ALNLGIEVIN TTDHLKFSKD CGRMLTRMWY CSYCQGLMMV KPCGGYCNVV MQGCMAGVVE IDKYWREYIL SLEELVNGMY RIYDMENVLL GLFSTIHDSI QYVQKNAGKL TTTIGKLCAH SQQRQYRSAY YPEDLFIDKK VLKVAHVEHE ETLSSRRREL IQKLKSFISF YSALPGYICS HSPVAENDTL CWNGQELVER YSQKAARNGM KNQFNLHELK MKGPEPVVSQ IIDKLKHINQ LLRTMSMPKG RVLDKNLDEE GFESGDCGDD EDECIGGSGD GMIKVKNQLR FLAELAYDLD VDDAPGNSQQ ATPKDNEIST FHNLGNVHHH HHHH
Pureté
> 90 % by SDS - PAGE
niveau d'endotoxine
< 1.0 EU per 1 microgram of protein (determined by LAL method)
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
Glypican 3 (GPC3)
Autre désignation
GPC3 (GPC3 Produits )
Synonymes
GPC3 Protein, sgb Protein, dgsx Protein, sdys Protein, sgbs Protein, oci-5 Protein, sgbs1 Protein, DGSX Protein, GTR2-2 Protein, MXR7 Protein, OCI-5 Protein, SDYS Protein, SGB Protein, SGBS Protein, SGBS1 Protein, Glypican-3 Protein, glypican 3 Protein, gpc3 Protein, GPC3 Protein, Gpc3 Protein
Sujet
GPC3, also known as glypican-3 isoform 2, is a member of the glypican family. It belongs to the glypican family and is highly expressed in lung, liver, and kidney. Also, it has tissue dependent. In some tissues, it acts as a tumor suppressor gene and an oncofetal protein. This protein is currently regarded as a tumor marker and potential target for immunotherapy. Recombinant human GPC3, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
61.8kDa (544aa) 50-70kDa (SDS-PAGE under reducing conditions.)
NCBI Accession
NP_004475
UniProt
P51654
Pathways
Glycosaminoglycan Metabolic Process
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