ALKBH3 Protein (AA 1-286) (His tag)

N° du produit ABIN667398

Détail du produit

Antigène: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Type de proteíne: Recombinant

Attributs du protein: AA 1-286

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette ALKBH3 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: ALKBH3, 1-286aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Autre désignation: ALKBH3 (ALKBH3 Produits)

Synonymes: ABH3 Protein, DEPC-1 Protein, DEPC1 Protein, PCA1 Protein, 1700108H04Rik Protein, 1810020C19Rik Protein, Abh3 Protein, mABH3 Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase L homeolog Protein, alkB homolog 3, alpha-ketoglutaratedependent dioxygenase Protein, alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase Protein, alkbh3.L Protein, ALKBH3 Protein, Alkbh3 Protein

Sujet: ALKBH3 is a member of the ALKB family of proteins and functions as a dioxygenase with a preference for RNA and single stranded DNA substrates. This protein repairs 1-methyladenine and 3-methylcytosine lesions in alkylated DNA and RNA and its activity is stimulated by ascorbate. ALKBH3 is expressed in a wide variety of tissues and localizes to the cytoplasm and the nucleus. Recombinant human ALKBH3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, ABH3, DEPC-1, DEPC1, PCA1. NCBI no.: NP_631917

Poids moléculaire: 37.9 kDa (325aa), confirmed by MALDI-TOF

Pathways: Réparation de l'ADN