C8G Protein (AA 21-202) (His tag)

N° du produit ABIN667575

Détail du produit

Antigène: C8G (Complement Component 8, gamma Polypeptide (C8G))

Type de proteíne: Recombinant

Attributs du protein: AA 21-202

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette C8G protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: C8G, 21-202 aa , Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by Bradford)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl.

Stock: 4 °C

Détail du antigène

Antigène: C8G (Complement Component 8, gamma Polypeptide (C8G))

Autre désignation: C8G (C8G Produits)

Synonymes: C8C Protein, complement C8 gamma chain Protein, complement component 8, gamma polypeptide Protein, C8G Protein, C8g Protein

Sujet: C8gamma, also known as C8G, is one of three polypeptides (along with C8 alpha and C8 beta) that constitutes C8, a component of the complement system. C8 participates in the formation of Membrane Attack Complex (MAC). Patients with deficiency in C8 are vulnerable to certain bacteria infection. C8gamma is a secreted protein that is able to bind retinol and belongs to the lipocalin family and calycin superfamily. It is synthesised in the liver, monocytes and fibroblast and functions to clear pathogens from an infected host. Recombinant human C8G protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: complement component 8, gamma polypeptide, C8C. NCBI no.: AAI13625

Poids moléculaire: 22.6 kDa (203aa), confirmed by MALDI-TOF

Pathways: Système du Complément