LAT Protein (AA 28-233) (His tag)

N° du produit ABIN7279583

Détail du produit

Antigène: LAT (Linker For Activation of T Cells (LAT))

Type de proteíne: Recombinant

Attributs du protein: AA 28-233

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette LAT protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: LAT, 28-233 aa , Human,His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford)

Buffer: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 1mM DTT

Stock: 4 °C

Détail du antigène

Antigène: LAT (Linker For Activation of T Cells (LAT))

Autre désignation: LAT (LAT Produits)

Synonymes: LAT Protein, lat Protein, LAT1 Protein, pp36 Protein, linker for activation of T-cells Protein, linker for activation of T cells Protein, LAT Protein, lat Protein, Lat Protein

Sujet: LAT is an integral membrane protein which is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells. Recombinant human LAT protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: linker for activation of T-cells family member 1 isoform b, LAT1, pp36. NCBI no.: NP_001014987

Poids moléculaire: 24.4 kDa (227aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway