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Leptin Protein (LEP)

LEP Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
N° du produit ABIN667698
  • Antigène Voir toutes Leptin (LEP) Protéines
    Leptin (LEP)
    Type de proteíne
    Recombinant
    Origine
    • 13
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    Souris
    Source
    • 33
    • 20
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    Leptin Mouse, Recombinant, E.coli
    Pureté
    > 95 % by SDS - PAGE
    Top Product
    Discover our top product LEP Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In Phosphate buffered saline pH7.4
    Stock
    4 °C
  • Antigène
    Leptin (LEP)
    Autre désignation
    Leptin (LEP Produits)
    Synonymes
    ob Protein, obese Protein, LEPD Protein, OB Protein, OBS Protein, leptin Protein, Lep Protein, LEP Protein, lep Protein
    Sujet
    Leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. Originally discovered in the mouse, the cDNA for leptin has been so far cloned from a variety of species including human, rat, cow, chicken, pig, sheep and dog. Recombinant mouse leptin was overexpressed as insoluble protein aggregate in E.coli and purified by FPLC gel-filtration chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. Synonyms: LEP, OB, OBS, Leptin Mouse, Obesity factor, Obese protein, Leptin,. NCBI no.: NP_032519
    Poids moléculaire
    16 kDa (147 aa), confirmed by MALDI-TOF.
    Pathways
    Signalistation JAK/STAT, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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