wu:fc05f09 Protein, wu:fi84b06 Protein, zgc:101724 Protein, MGC53390 Protein, MGC80084 Protein, MGC132077 Protein, PTP4A2 Protein, ptp4a2 Protein, Prl-2 Protein, HH13 Protein, HH7-2 Protein, HU-PP-1 Protein, OV-1 Protein, PRL-2 Protein, PRL2 Protein, PTP4A Protein, PTPCAAX2 Protein, ptp-IV1a Protein, ptp-IV1b Protein, protein tyrosine phosphatase type IVA, member 2b Protein, protein tyrosine phosphatase 4a2 Protein, protein tyrosine phosphatase type IVA, member 2 Protein, protein tyrosine phosphatase type IVA, member 2 L homeolog Protein, ptp4a2b Protein, ptp4a2 Protein, PTP4A2 Protein, ptp4a2.L Protein, Ptp4a2 Protein
Sujet
Protein tyrosine phosphatase type IVA 2 isoform 1, also known as PTP4A2, belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTP4A2 is localized to the early endosome that play regulatory roles in a variety of cellular processes. This protein was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Recombinant human PTP4A2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Protein tyrosine phosphatase type IVA 2 isoform 1, HH13, HH7-2, HU-PP-1, OV-1, PRL-2, PRL2, ptp-IV1a, ptp-IV1b, PTP4A, PTPCAAX2, EC 3.1.3.48 , HH13 , HH7 2 , HUPP 1 , HUPP1 , OV 1 , OV1 , PRL 2 , PRL2 , Protein tyrosine phosphatase 4a2 , Protein tyrosine phosphatase of regenerating liver 2 , Protein tyrosine phosphatase type IVA member 2 isoform 1 , PTP (CAAXII) , ptp IV1a , ptp IV1b , PTP4A , PTPCAAX2 ,. NCBI no.: NP_536316