PFDN6 Protein (AA 1-129) (His tag)

N° du produit ABIN667890

Détail du produit

Antigène: PFDN6 (Prefoldin Subunit 6 (PFDN6))

Type de proteíne: Recombinant

Attributs du protein: AA 1-129

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette PFDN6 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Attributs du produit: PFDN6, 1-129aa, Human, His tag, E.coli

Pureté: > 95 % by SDS - PAGE

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/ml (determined by BCA assay)

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M NaCl, 1mM DTT, 10% glycerol

Stock: 4 °C

Détail du antigène

Antigène: PFDN6 (Prefoldin Subunit 6 (PFDN6))

Autre désignation: PFDN6 (PFDN6 Produits)

Synonymes: hke2 Protein, ke-2 Protein, pfd6 Protein, h2-ke2 Protein, pfdn6a Protein, 23.m05913 Protein, H-2Ke2 Protein, Ke-2 Protein, Pfdn6 Protein, H2-KE2 Protein, HKE2 Protein, KE-2 Protein, PFD6 Protein, zgc:66282 Protein, pfdn6 Protein, pfdn6b Protein, Ke2 Protein, prefoldin subunit 6 S homeolog Protein, prefoldin subunit 6 (predicted) Protein, prefoldin subunit 6 Protein, prefoldin subunit 6 L homeolog Protein, pfdn6.S Protein, SPAC3A11.13 Protein, BBOV_IV004800 Protein, AOR_1_2254174 Protein, CMU_042830 Protein, pfdn6 Protein, Pfdn6 Protein, PFDN6 Protein, pfdn6.L Protein

Sujet: PFDN6, also known as HKE2 or PFD6, is a subunit of the heteromeric prefoldin complex that chaperones nascent actin and alpha- and beta-tubulin chains pending their transfer to the cytosolic chaperonin containing TCP1 (CCT) complex. It binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it and binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Recombinant human PFDN6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: Prefoldin subunit 6, H2-KE2, HKE2, KE-2, MGC70744, PFD6. NCBI no.: NP¬_055075

Poids moléculaire: 16.7 kDa (149aa) confirmed by MALDI-TOF

Pathways: Unfolded Protein Response