IL4 Receptor Protein (AA 26-232) (Fc Tag)
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- Antigène Voir toutes IL4 Receptor (IL4R) Protéines
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 26-232
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL4 Receptor protéine est marqué à la Fc Tag.
- Séquence
- AA 26-232
- Pureté
- >95 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL4R Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Tris with Glycine, Arginine and NaCl, pH 7.5
- Conseil sur la manipulation
- Please avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
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- Antigène
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- Autre désignation
- IL-4 R alpha (IL4R Produits)
- Synonymes
- IL4R Protein, il-4ra Protein, zgc:113063 Protein, CD124 Protein, IL-4RA Protein, IL4RA Protein, Il4ra Protein, IL4 Protein, Il4r Protein, interleukin 4 receptor Protein, interleukin 4 receptor, tandem duplicate 1 Protein, interleukin 4 receptor, alpha Protein, IL4R Protein, il4r.1 Protein, Il4r Protein, Il4ra Protein
- Sujet
- IL-4 R alpha is also known as IL4R, CD124, IL-4RA.This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitis, asthma, or eczema. The binding of IL-4 or IL-13 to the IL-4 receptor on the surface of macrophages results in the alternative activation of those macrophages. Interleukin-4 receptor has been shown to interact with SHC1.
- Poids moléculaire
- 50.4 kDa
- NCBI Accession
- NP_000409
- Pathways
- Signalistation JAK/STAT, Positive Regulation of Immune Effector Process
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