IL4 Receptor Protein (AA 24-232) (Fc Tag)
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- Antigène Voir toutes IL4 Receptor (IL4R) Protéines
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 24-232
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL4 Receptor protéine est marqué à la Fc Tag.
- Fonction
- Human IL-4 R alpha/CD124 Protein
- Séquence
- Gly24-His232
- Attributs du produit
- Recombinant Human IL-4 R alpha/CD124 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly24-His232.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-4, No Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Human IL-4 R alpha, hFc Tag with the EC50 of 9.8ng/ml determined by ELISA. See testing image for detail.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- Autre désignation
- IL-4 R alpha (IL4R Produits)
- Synonymes
- IL4R Protein, il-4ra Protein, zgc:113063 Protein, CD124 Protein, IL-4RA Protein, IL4RA Protein, Il4ra Protein, IL4 Protein, Il4r Protein, interleukin 4 receptor Protein, interleukin 4 receptor, tandem duplicate 1 Protein, interleukin 4 receptor, alpha Protein, IL4R Protein, il4r.1 Protein, Il4r Protein, Il4ra Protein
- Sujet
- Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family.The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
- Poids moléculaire
- 50.7 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- Pathways
- Signalistation JAK/STAT, Positive Regulation of Immune Effector Process
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