IL4 Receptor Protein (AA 26-232) (His tag)
-
- Antigène Voir toutes IL4 Receptor (IL4R) Protéines
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 26-232
-
Origine
- Cynomolgus
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL4 Receptor protéine est marqué à la His tag.
- Fonction
- Cynomolgus IL-4 R alpha/CD124 Protein
- Séquence
- Met26-Arg232
- Attributs du produit
- Recombinant Cynomolgus IL-4 R alpha/CD124 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Met26-Arg232.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human IL-4, No Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Cynomolgus IL-4 R alpha, His Tag with the EC50 of 36.5ng/ml determined by ELISA. The affinity constant of 13.48 nM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product IL4R Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- Autre désignation
- IL-4 R alpha (IL4R Produits)
- Synonymes
- IL4R Protein, il-4ra Protein, zgc:113063 Protein, CD124 Protein, IL-4RA Protein, IL4RA Protein, Il4ra Protein, IL4 Protein, Il4r Protein, interleukin 4 receptor Protein, interleukin 4 receptor, tandem duplicate 1 Protein, interleukin 4 receptor, alpha Protein, IL4R Protein, il4r.1 Protein, Il4r Protein, Il4ra Protein
- Sujet
- Interleukin 4 Receptor alpha (IL-4 Ra), also known as CD124 and BSF receptor, is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family.The effects of IL-4 are mediated after binding to high affinity receptor complexes present on hematopoietic as well as non-hematopoietic cells.
- Poids moléculaire
- 24.84 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result.
- UniProt
- G7Q0S7
- Pathways
- Signalistation JAK/STAT, Positive Regulation of Immune Effector Process
-