CD3D Protein (His tag)
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- Antigène Voir toutes CD3D Protéines
- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
- Type de proteíne
- Recombinant
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CD3D protéine est marqué à la His tag.
- Fonction
- Recombinant human CD3D protein with C-terminal 6xHis tag
- Specificité
- CD3D (Phe22-Ala105) 6xHis tag
- Attributs du produit
- Extracellular Domain Protein
- Purification
- affinity purification
- Pureté
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product CD3D Protéine
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with deionized water
- Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- Agent conservateur
- Without preservative
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Date de péremption
- 12 months
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- Antigène
- CD3D (CD3d Molecule, delta (CD3-TCR Complex) (CD3D))
- Autre désignation
- CD3D (CD3D Produits)
- Synonymes
- CD3-DELTA Protein, T3D Protein, CD3 Protein, T3d Protein, CD3d molecule Protein, CD3 antigen, delta polypeptide Protein, CD3D Protein, Cd3d Protein
- Sujet
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Synonymes: CD3D,CD3-DELTA,T3D
Description: The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. - Poids moléculaire
- predicted molecular mass of 10.4 kDa after removal of the signal peptide. The apparent molecular mass of CD3D-His is 15-25 kDa due to glycosylation.
- UniProt
- P04234
- Pathways
- TCR Signaling, CXCR4-mediated Signaling Events
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