+49 (0)241 95 163 153
+49 (0)241 95 163 155

Syndecan 1 Protein (SDC1) (AA 23-254) (Fc Tag,AVI tag,Biotin)

SDC1 Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
N° du produit ABIN6973274
  • Antigène Voir toutes Syndecan 1 (SDC1) Protéines
    Syndecan 1 (SDC1)
    Type de proteíne
    Activité biologique
    Attributs du protein
    AA 23-254
    • 22
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 17
    • 11
    • 4
    • 4
    • 3
    • 1
    HEK-293 Cells
    Cette Syndecan 1 protéine est marqué à la Fc Tag,AVI tag,Biotin.
    AA 23-254
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    Attributs du produit
    Biotinylated Human Syndecan-1 Protein, His,Avitag™
    >90 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product SDC1 Protéine
  • Commentaires

    Ready-to-use Avitag™ biotinylated protein:
    The product is exclusively produced using the Avitag™ technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    For Research Use only
  • Format
    PBS, pH 7.4
    -20 °C
  • Antigène
    Syndecan 1 (SDC1)
    Autre désignation
    Syndecan-1 (SDC1 Produits)
    CG10497 Protein, CT27296 Protein, Dmel\\CG10497 Protein, Dsyn Protein, Syd Protein, Syn Protein, dSdc Protein, l(2)10608 Protein, sdc Protein, syd Protein, syn Protein, Syn1 Protein, cd138 Protein, synd1 Protein, xSyn1 Protein, syndecan1 Protein, Syndecan-1 Protein, XSyndecan-1 Protein, SDC1 Protein, CD138 Protein, SDC Protein, SYND1 Protein, syndecan Protein, AA408134 Protein, AA409076 Protein, Sstn Protein, Synd Protein, Synd1 Protein, syn-1 Protein, HSPG Protein, SYNDECA Protein, Syndecan Protein, Syndecan Protein, syndecan 1 Protein, Sdc Protein, sdc1 Protein, SDC1 Protein, Sdc1 Protein
    Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.
    Poids moléculaire
    52.0 kDa
    Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism
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