GPC1 Protein (Ser486Ala-Mutant, Ser488Ala-Mutant, Ser490Ala-Mutant) (His tag)

N° du produit ABIN7125966

Détail du produit

Antigène: GPC1 (Glypican 1 (GPC1))

Type de proteíne: Recombinant

Attributs du protein: Ser486Ala-Mutant, Ser488Ala-Mutant, Ser490Ala-Mutant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GPC1 protéine est marqué à la His tag.

Fonction: Human Glypican 1 / GPC1 (S486A, S488A, S490A) Protein, His Tag (MALS verified)

Séquence: Asp 24 - Ser 530

Attributs du produit: Human Glypican 1 (S486A, S488A, S490A), His Tag is expressed from human 293 cells (HEK293). It contains AA Asp 24 - Ser 530 (Accession # P35052-1 (S486A, S488A, S490A).

Pureté: >95 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 1.0 EU per μg by the LAL method.

Classe de qualité: MALS verified

Information d'application

Indications d'application: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 57.9 kDa. The protein migrates as 58-61 kDa under reducing (R) condition due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 50 mM Tris, 150 mM NaCl, pH 7.5

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: GPC1 (Glypican 1 (GPC1))

Autre désignation: Glypican 1 / GPC1 (GPC1 Produits)

Synonymes: gpc1 Protein, zgc:63947 Protein, GPC1 Protein, Glypican-1 Protein, glypican Protein, AI462976 Protein, HSPG M12 Protein, HSPGM12 Protein, glypican 1b Protein, glypican 1 Protein, gpc1b Protein, GPC1 Protein, gpc1 Protein, Gpc1 Protein

Sujet: Synonyms: Glypican 1,GPC1,
Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Poids moléculaire: 57.9 kDa

NCBI Accession: NP_002072

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation