BAX Protein (His tag)

N° du produit ABIN7318194

Détail du produit

Antigène: BAX (BCL2-Associated X Protein (BAX))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BAX protéine est marqué à la His tag.

Fonction: Recombinant Human BAX/BCL2L4 Protein (His Tag)

Séquence: Met 1-Gln171

Attributs du produit: Recombinant Human BCL2-associated X protein is produced by our E.coli expression system and the target gene encoding Met1-Gln171 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.

Pureté: > 95 % as determined by reducing SDS-PAGE.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,2 mM EDTA,5 % Threhalose,30 % Glycerol, pH 7.4.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: BAX (BCL2-Associated X Protein (BAX))

Autre désignation: BAX/BCL2L4 (BAX Produits)

Synonymes: BAX-ALPHA Protein, bax-A Protein, xBax Protein, xlbax Protein, BAX Protein, bax Protein, fj16e01 Protein, wu:fc50b10 Protein, wu:fj16e01 Protein, BCL2L4 Protein, zgc:112983 Protein, BCL2 associated X, apoptosis regulator Protein, BCL2-associated X protein L homeolog Protein, BCL2-associated X protein Protein, bcl2-associated X protein, a Protein, bcl2-associated X protein, b Protein, BAX Protein, bax.L Protein, bax Protein, baxa Protein, Bax Protein, baxb Protein

Sujet:

Background: Apoptosis Regulator BAX (BAX) belongs to the Bcl-2 family. BAX exists as a homodimer and is expressed in a wide variety of tissues. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa). Although both isoforms contain BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. BAX accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX also promotes activation of CASP3, and thereby apoptosis.

Synonym: Apoptosis Regulator BAX, Bcl-2-Like Protein 4, Bcl2-L-4, BAX, BCL2L4

Poids moléculaire: 22.1 kDa

UniProt: Q07812

Pathways: Signalisation p53, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response