SCARB1 Protein (His tag)

N° du produit ABIN7320319

Détail du produit

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette SCARB1 protéine est marqué à la His tag.

Fonction: Recombinant Mouse SR-BI/CD36L1 Protein (His Tag)

Séquence: Pro 33-Val 440

Attributs du produit: A DNA sequence encoding the mature form of mouse SRB1 (NP_058021.1) extracellular domain (Pro 33-Val 440) was fused with a polyhistidine tag at the C-terminus.

Pureté: > 90 % as determined by SDS-PAGE

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from sterile PBS, pH 7.4

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Autre désignation: SR-BI/CD36L1 (SCARB1 Produits)

Synonymes: cb1015 Protein, SCARB1 Protein, Scarb1 Protein, CD36L1 Protein, CLA-1 Protein, CLA1 Protein, HDLQTL6 Protein, SR-BI Protein, SRB1 Protein, AI120173 Protein, CD36 Protein, Cd36l1 Protein, Cla-1 Protein, Cla1 Protein, D5Ertd460e Protein, Hdlq1 Protein, Hlb398 Protein, SR-B1 Protein, SRBI Protein, Srb1 Protein, mSR-BI Protein, scavenger receptor class B, member 1 Protein, scavenger receptor class B member 1 Protein, scarb1 Protein, SCARB1 Protein, Scarb1 Protein, CpipJ_CPIJ014332 Protein, CpipJ_CPIJ019101 Protein

Sujet:

Background: Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane. SCARB1 is proposed as a receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells, and is involved in a wide variety of physilogical processes. As a key component in the reverse cholesterol transport pathway, SCARB1 binds high density lipoproteins (HDLs) and mediates selective cholesterol uptake by a mechanism distinct from the LDL pathway. High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. SCARB1 may thus serve as a useful marker that predicts variation in baseline lipid levels and postprandial lipid response. The mouse SCARB1 has been shown to exert actions in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.

Synonym: AI120173;CD36;Cd36l1;Cla-1;Cla1;D5Ertd460e;Hdlq1;Hlb398;mSR-BI;SR-B1;SR-BI;Srb1;SRBI

Poids moléculaire: 47 kDa

NCBI Accession: NP_058021

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome