SCARB2 Protein (His tag)
-
- Antigène Voir toutes SCARB2 Protéines
- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
- Type de proteíne
- Recombinant
-
Origine
- Souris
-
Source
- Human Cells
- Purification/Conjugué
- Cette SCARB2 protéine est marqué à la His tag.
- Fonction
- Recombinant Mouse SCARB2/LIMPII Protein (His Tag)
- Séquence
- Arg27-Thr432
- Attributs du produit
- Recombinant Mouse Lysosomal Integral Membrane Protein II is produced by our Mammalian expression system and the target gene encoding Arg27-Thr432 is expressed with a Fc tag at the C-terminus.
- Pureté
- > 95 % as determined by SDS-PAGE
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SCARB2 Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-Citrate, 0.3M NaCl, pH 6.5.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Antigène
- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
- Autre désignation
- SCARB2/LIMPII (SCARB2 Produits)
- Synonymes
- cd36l2 Protein, fi13c07 Protein, chunp6914 Protein, wu:fi13c07 Protein, SCARB2 Protein, scarb2 Protein, AMRF Protein, CD36L2 Protein, EPM4 Protein, HLGP85 Protein, LGP85 Protein, LIMP-2 Protein, LIMPII Protein, SR-BII Protein, 9330185J12Rik Protein, Cd36l2 Protein, MLGP85 Protein, LimpII Protein, scavenger receptor class B, member 2a Protein, scavenger receptor class B member 2 Protein, scavenger receptor class B, member 2 Protein, scarb2a Protein, SCARB2 Protein, scarb2 Protein, Scarb2 Protein
- Sujet
-
Background: Lysosome membrane protein II (LIMPII),also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is identified as a receptor for EV71 (human enterovirus species A, Enterovirus 71) and CVA16 (coxsackievirus A16) which are most frequently associated with hand, foot and mouth disease (HFMD). Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. In addition, LIMPII also has been shown to bind thrombospondin-1, may contribute to the pro-adhesive changes of activated platelets during coagulation, and inflammation.
Synonym: CD36L2,9330185J12Rik,Cd36l2,LGP85,LIMP-2,MLGP85,Lysosome membrane protein 2, 85 kDa lysosomal membrane sialoglycoprotein, LGP85, Lysosome membrane protein II, LIMP II, Scavenger receptor class B member 2
- Poids moléculaire
- 73.4 kDa
- UniProt
- O35114
-