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NEU1 Protein (His tag)

NEU1 Origine: Humain Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7319034
  • Antigène Voir toutes NEU1 Protéines
    NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
    Type de proteíne
    Recombinant
    Origine
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification/Conjugué
    Cette NEU1 protéine est marqué à la His tag.
    Fonction
    Recombinant Human Sialidase-1/NEU-1 Protein (His Tag)
    Séquence
    Glu48-Leu415
    Attributs du produit
    Recombinant Human N-acetyl-alpha-Neuraminidase 1 is produced by our Mammalian expression system and the target gene encoding Glu48-Leu415 is expressed with a 6His tag at the C-terminus.
    Pureté
    > 95 % as determined by reducing SDS-PAGE.
    niveau d'endotoxine
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product NEU1 Protéine
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Stock
    -20 °C
    Stockage commentaire
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène
    NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
    Autre désignation
    Sialidase-1/NEU-1 (NEU1 Produits)
    Synonymes
    NANH Protein, NEU Protein, SIAL1 Protein, MGC81958 Protein, AA407268 Protein, AA407316 Protein, Aglp Protein, Apl Protein, Bat-7 Protein, Bat7 Protein, G9 Protein, Map-2 Protein, Neu Protein, Neu-1 Protein, neuraminidase 1 Protein, neuraminidase 1 (lysosomal sialidase) L homeolog Protein, NEU1 Protein, neu1.L Protein, neu1 Protein, Neu1 Protein
    Sujet

    Background: Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues, it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.

    Synonym: Sialidase-1, Acetylneuraminyl Hydrolase, G9 Sialidase, Lysosomal Sialidase, N-Acetyl-Alpha-Neuraminidase 1, NEU1, NANH

    Poids moléculaire
    41.3 kDa
    UniProt
    Q99519
    Pathways
    SARS-CoV-2 Protein Interactome
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