EPH Receptor B2 Protein (EPHB2) (AA 19-542) (His tag)
-
- Antigène Voir toutes EPH Receptor B2 (EPHB2) Protéines
- EPH Receptor B2 (EPHB2)
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 19-542
-
Origine
- Cynomolgus
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette EPH Receptor B2 protéine est marqué à la His tag.
- Fonction
- Cynomolgus EPHB2 Protein
- Séquence
- Val19-Pro542
- Attributs du produit
- Recombinant Cynomolgus EPHB2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val19-Pro542.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus EPHB2, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-EPHB2 Antibody, hFc Tag with the EC50 of 8.3ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product EPHB2 Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- EPH Receptor B2 (EPHB2)
- Autre désignation
- EPHB2 (EPHB2 Produits)
- Synonymes
- CAPB Protein, DRT Protein, EK5 Protein, EPHT3 Protein, ERK Protein, Hek5 Protein, PCBC Protein, Tyro5 Protein, ERK2 Protein, ERT1 Protein, MAPK2 Protein, P42MAPK Protein, PRKM1 Protein, PRKM2 Protein, p38 Protein, p40 Protein, p41 Protein, p41mapk Protein, RGD1564232 Protein, Cek5 Protein, Drt Protein, ETECK Protein, Erk Protein, Nuk Protein, Prkm5 Protein, Qek5 Protein, Sek3 Protein, cek5 Protein, ephb2 Protein, xEphB2 Protein, si:ch73-160e9.1 Protein, tpx2 Protein, wu:fb09e10 Protein, wu:fc64a03 Protein, wu:fi18g12 Protein, zgc:112296 Protein, EPH receptor B2 Protein, mitogen-activated protein kinase 1 Protein, Eph receptor B2 Protein, EPH receptor B2 L homeolog Protein, eph receptor B2a Protein, eph receptor B2b Protein, EPHB2 Protein, MAPK1 Protein, Ephb2 Protein, ephb2.L Protein, ephb2a Protein, ephb2b Protein
- Sujet
- EphB2, a receptor tyrosine kinase for ephrin ligands, is overexpressed in various cancers and plays an important role in tumor progression. EPHB2 promotes endothelial-mesenchymal transition (EMT) and elicits associated pathologic characteristics of glioblastoma multiforme (GBM) such as invasion and migration. EPHB2 is epigenetically overexpressed in hypoxia, a condition highly prevalent in malignancy. Furthermore, HIF-2α is required for EPHB2 stabilization by hypoxia.
- Poids moléculaire
- 59.09 kDa. Due to glycosylation, the protein migrates to 65-75 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A7N9CQH5
- Pathways
- Signalisation RTK, Regulation of long-term Neuronal Synaptic Plasticity, S100 Proteins
-