FGFR4 Protein (His-Avi Tag,Biotin)

N° du produit ABIN7274632

Détail du produit

Antigène: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette FGFR4 protéine est marqué à la His-Avi Tag,Biotin.

Séquence: Leu22-Asp369

Pureté: > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.

Stock: 4 °C,-80 °C

Stockage commentaire: Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

Autre désignation: FGFR4 (FGFR4 Produits)

Synonymes: FGFR4 Protein, XFGFR-4 Protein, XFGFR-4a Protein, cd334 Protein, fgfr-4 Protein, jtk2 Protein, tkf Protein, xfgfr4 Protein, CD334 Protein, JTK2 Protein, TKF Protein, Fgfr-4 Protein, etID309818.21 Protein, wu:fc13h10 Protein, zgc:111935 Protein, fgfr-4c Protein, fgfr4 Protein, fibroblast growth factor receptor 4 Protein, fibroblast growth factor receptor 4 S homeolog Protein, FGFR4 Protein, fgfr4 Protein, Fgfr4 Protein, fgfr4.S Protein

Sujet: CD334, FGF R4, FGFR4, FGFR-4, MGC20292, JTK2, TKF,Fibroblast growth factor receptor 4 (FGF R4), also known as CD334, is a 110 kDa glycosylated transmembrane receptor tyrosine kinase.Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays a role in the regulation of cell proliferation, differentiation and migration, and in regulation of lipid metabolism, bile acid biosynthesis, glucose uptake, vitamin D metabolism and phosphate homeostasis. Required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19.

Poids moléculaire: 41.4 kDa. Due to glycosylation, the protein migrates to 55-72 kDa based on Tris-Bis PAGE result.

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding