IL-6 Protein (AA 28-212) (His tag)
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- Antigène Voir toutes IL-6 (IL6) Protéines
- IL-6 (IL6) (Interleukin 6 (IL6))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 28-212
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Origine
- Cynomolgus
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL-6 protéine est marqué à la His tag.
- Fonction
- Cynomolgus IL-6 Protein
- Séquence
- Ala28-Met212
- Attributs du produit
- Recombinant Cynomolgus IL-6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala28-Met212.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus IL-6, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human IL-6 R alpha, hFc Tag with the EC50 of 38.9ng/ml determined by ELISA. See testing image for detail.
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- Discover our top product IL6 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IL-6 (IL6) (Interleukin 6 (IL6))
- Autre désignation
- IL-6 (IL6 Produits)
- Synonymes
- BSF2 Protein, HGF Protein, HSF Protein, IFNB2 Protein, IL-6 Protein, Il-6 Protein, ILg6 Protein, Ifnb2 Protein, il6 Protein, CHIL-6 Protein, interleukin 6 Protein, interleukin-6 Protein, IL6 Protein, Il6 Protein, il-6 Protein, IL-6 Protein
- Sujet
- IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein.
- Poids moléculaire
- 22.06 kDa. Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result.
- UniProt
- P79341
- Pathways
- Signalisation TLR, Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis, Cancer Immune Checkpoints, Inflammasome
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