Notch1 Protein (His-Avi Tag,Biotin)
-
- Antigène Voir toutes Notch1 (NOTCH1) Protéines
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
- Type de proteíne
- Recombinant
-
Origine
- Humain
-
Source
- HEK-293 Cells
- Purification/Conjugué
- Cette Notch1 protéine est marqué à la His-Avi Tag,Biotin.
- Séquence
- Ala19-Gln526
- Pureté
- > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product NOTCH1 Protéine
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- Notch1 (NOTCH1) (Notch 1 (NOTCH1))
- Autre désignation
- Notch 1 (NOTCH1 Produits)
- Synonymes
- notch1 Protein, NOTCH1 Protein, hn1 Protein, tan1 Protein, notch Protein, xotch Protein, xnotch Protein, notch-1 Protein, xnotch1 Protein, TAN1 Protein, hN1 Protein, 9930111A19Rik Protein, Mis6 Protein, N1 Protein, Tan1 Protein, lin-12 Protein, NOTCH Protein, Xotch Protein, notch1-a Protein, notch 1 Protein, fibropellin-1 Protein, Notch homolog 1, translocation-associated (Drosophila) Protein, Notch homolog 1, translocation-associated Protein, notch 1 S homeolog Protein, notch1 Protein, LOC100631526 Protein, NOTCH1 Protein, Notch1 Protein, notch1.S Protein
- Sujet
- Notch-1, TAN1, NOTCH1, 9930111A19Rik, lin-12, Mis6, N1,Human Notch-1 is a 300 kDa type I transmembrane glycoprotein that is one of four human Notch homologues involved in developmental processes.Notch-1 functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
- Poids moléculaire
- 56.5 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.
- UniProt
- P46531
- Pathways
- Signalisation Notch, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
-