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Oncostatin M Protein (OSM) (His-Avi Tag,Biotin)

OSM Origine: Humain Hôte: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
N° du produit ABIN7275380
  • Antigène Voir toutes Oncostatin M (OSM) Protéines
    Oncostatin M (OSM)
    Type de proteíne
    Recombinant
    Origine
    • 25
    • 7
    • 4
    • 3
    • 1
    • 1
    Humain
    Source
    • 22
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Oncostatin M protéine est marqué à la His-Avi Tag,Biotin.
    Séquence
    Ala26-Arg221
    Pureté
    > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product OSM Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/mL is recommended (usually we use 1 mg/mL solution for lyophilization). Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.
    Stock
    4 °C,-80 °C
    Stockage commentaire
    Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Oncostatin M (OSM)
    Autre désignation
    Oncostatin M (OSM Produits)
    Synonymes
    OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
    Sujet
    Oncostatin M, OSM, MGC20461,OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.
    Poids moléculaire
    25.1 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
    UniProt
    P13725
    Pathways
    Signalistation JAK/STAT, Negative Regulation of Hormone Secretion
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