VEGFR2/CD309 Protein (AA 20-764) (mFc Tag,Biotin)
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- Antigène Voir toutes VEGFR2/CD309 (VEGFR2) Protéines
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 20-764
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette VEGFR2/CD309 protéine est marqué à la mFc Tag,Biotin.
- Fonction
- Biotinylated Human VEGF R2/KDR Protein (Primary Amine Labeling)
- Séquence
- Ala20-Glu764
- Attributs du produit
- Recombinant Biotinylated Human VEGF R2/KDR Protein (Primary Amine Labeling) is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Ala20-Glu764.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human VEGF165, No Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Human VEGF R2, mFc Tag with the EC50 of 0.14μg/ml determined by ELISA. See testing image for detail.
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- Discover our top product VEGFR2 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
- Autre désignation
- VEGF R2 (VEGFR2 Produits)
- Synonymes
- CD309 Protein, FLK1 Protein, VEGFR Protein, VEGFR2 Protein, 6130401C07 Protein, Flk-1 Protein, Flk1 Protein, Krd-1 Protein, Ly73 Protein, VEGFR-2 Protein, sVEGFR-2 Protein, Vegfr-2 Protein, FLK-1 Protein, flk-1 Protein, vegfr-2 Protein, KDR Protein, FLK/KDR Protein, flk1 Protein, flk1b Protein, kdrb Protein, si:busm1-205d10.1 Protein, si:ch211-254j6.1 Protein, si:ch211-278f21.4 Protein, wu:fc31a09 Protein, fk52c05 Protein, flk Protein, kdr Protein, kdra Protein, vegfr2 Protein, vegfr4 Protein, vegr2 Protein, wu:fk52c05 Protein, kinase insert domain receptor Protein, kinase insert domain protein receptor Protein, vascular endothelial growth factor receptor kdr-like Protein, kinase insert domain receptor (a type III receptor tyrosine kinase) Protein, kinase insert domain receptor like Protein, KDR Protein, Kdr Protein, LOC100136647 Protein, kdr Protein, kdrl Protein
- Sujet
- Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, the regulation of angiogenesis, cell survival, cell migration, macrophage function, chemotaxis, and cancer cell invasion. The tyrosine kinase receptor vascular endothelial growth factor receptor 2 (VEGFR2) is a key regulator of angiogenesis.
- Poids moléculaire
- 110 kDa. Due to glycosylation, the protein migrates to 135-160 kDa based on Tris-Bis PAGE result.
- Pathways
- Signalisation RTK, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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