IFNAR1 Protein (mFc Tag)

N° du produit ABIN7490868

Détail du produit

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IFNAR1 protéine est marqué à la mFc Tag.

Fonction: Recombinant human IFNAR1 Protein with C-terminal Mouse Fc tag

Specificité: IFNAR1 (Lys28-Lys436) mFc (Pro99-Lys330)

Attributs du produit: Extracellular Domain Protein

Pureté: The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Autre désignation: IFNAR1 (IFNAR1 Produits)

Synonymes: ifnar1 Protein, IFNAR1 Protein, CD118 Protein, Ifar Protein, Ifnar Protein, Ifrc Protein, Infar Protein, AVP Protein, IFN-alpha-REC Protein, IFNAR Protein, IFNBR Protein, IFRC Protein, IFN-R-1 Protein, interferon alpha and beta receptor subunit 1 Protein, interferon-alpha/beta receptor alpha chain-like Protein, interferon (alpha and beta) receptor 1 Protein, interferon alpha/beta receptor 1 Protein, IFNAR1 Protein, ifnar1 Protein, Ifnar1 Protein, LOC609830 Protein

Sujet: Interferon alpha/beta receptor 1,IFN-R-1,IFN-alpha/beta receptor 1,CRF2-1,Type I interferon receptor 1
Description: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family and functions as an antiviral factor. [provided by RefSeq, Jul 2020]

Poids moléculaire: predicted molecular mass of 73 kDa after removal of the signal peptide. The apparent molecular mass of IFNAR1-mFc is 100-130 kDa due to glycosylation.

UniProt: P17181

Pathways: Signalistation JAK/STAT, Hepatitis C