FZD7 Protéine

N° du produit ABIN7491647

Détail du produit

Antigène: FZD7 (Frizzled Family Receptor 7 (FZD7))

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human FZD7 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: FZD7 (Frizzled Family Receptor 7 (FZD7))

Autre désignation: FZD7 (FZD7 Produits)

Synonymes: FzE3 Protein, Fz-7 Protein, Xfz7 Protein, frizzled-7 Protein, frizzled7 Protein, frz-7 Protein, frz7 Protein, fz7 Protein, fzd7-a Protein, fzd7-b Protein, fze3 Protein, Fz7 Protein, cFz-7 Protein, fb38g02 Protein, fc44b09 Protein, fz13 Protein, fz7a Protein, fz7b Protein, wu:fb38g02 Protein, wu:fc44b09 Protein, zg13 Protein, frizzled class receptor 7 Protein, frizzled class receptor 7 L homeolog Protein, frizzled class receptor 7b Protein, FZD7 Protein, fzd7.L Protein, fzd7 Protein, Fzd7 Protein, fzd7b Protein

Sujet: FzE3Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]

Poids moléculaire: The human full length FZD7 protein has a MW of 63.4 kDa

UniProt: O75084

Pathways: Signalisation WNT, Stem Cell Maintenance