TRKA Protein (AA 33-417) (His tag)

N° du produit ABIN7504556

Détail du produit

Antigène: TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Type de proteíne: Recombinant

Attributs du protein: AA 33-417

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TRKA protéine est marqué à la His tag.

Fonction: Human TrkA Protein

Séquence: Ala33-Gly417

Attributs du produit: Recombinant Human TrkA Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala33-Gly417.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))

Autre désignation: TrkA (NTRK1 Produits)

Synonymes: MTC Protein, TRK Protein, TRK1 Protein, TRKA Protein, Trk-A Protein, p140-TrkA Protein, CDHF12 Protein, CDHR16 Protein, HSCR1 Protein, MEN2A Protein, MEN2B Protein, MTC1 Protein, PTC Protein, RET-ELE1 Protein, RET51 Protein, Trk Protein, C80751 Protein, Tkr Protein, TrkA Protein, trk Protein, trka Protein, CTRKA Protein, trkA Protein, neurotrophic receptor tyrosine kinase 1 Protein, ret proto-oncogene Protein, neurotrophic tyrosine kinase, receptor, type 1 Protein, NTRK1 Protein, RET Protein, Ntrk1 Protein, ntrk1 Protein

Sujet: TrkA, a tyrosine kinase receptor, is an essential component of the nerve growth factor (NGF) response pathway. The binding of NGF to the receptor induces receptor autophosphorylation and activation of intracellular signaling pathways, resulting in diverse biological effects.

Poids moléculaire: 43.00 kDa. Due to glycosylation, the protein migrates to 70-100 kDa based on Tris-Bis PAGE result.

Pathways: Signalisation RTK, Neurotrophin Signaling Pathway, cAMP Metabolic Process