PUMA Protein (AA 1-193) (His tag)
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- Antigène Voir toutes PUMA (BBC3) Protéines
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-193
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette PUMA protéine est marqué à la His tag.
- Séquence
- Met1-Asn193
- Attributs du produit
- A DNA sequence encoding the Human PUMA/BBC3 (Q9BXH1-1) (1M-193N) was expressed with a polyhistidine tag at the N-terminus.
- Pureté
- >90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BBC3 Protéine
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- Commentaires
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used as Immunogen for (ABIN6999884, ABIN7234184, ABIN7234185 and ABIN7234186)
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- Autre désignation
- PUMA (BBC3 Produits)
- Synonymes
- BBC3 Protein, Puma Protein, JFY-1 Protein, JFY1 Protein, PUMA Protein, PUMA/JFY1 Protein, BCL2 binding component 3 Protein, Bcl-2 binding component 3 Protein, BBC3 Protein, Bbc3 Protein, bbc3 Protein
- Sujet
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Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Synonym: BBC 3, Bbc3, BBC3_HUMAN, BCL 2 binding component 3, Bcl-2-binding component 3, BCL2 binding component 3, JFY 1, JFY-1, JFY1, p53 up regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1
- Poids moléculaire
- 20.1 kDa
- Pathways
- Signalisation p53, Positive Regulation of Endopeptidase Activity
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