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PUMA Protein (AA 1-193) (His tag)

BBC3 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >90 % as determined by reducing SDS-PAGE.
N° du produit ABIN7504951
  • Antigène Voir toutes PUMA (BBC3) Protéines
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-193
    Origine
    • 7
    • 2
    • 1
    Humain
    Source
    • 4
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette PUMA protéine est marqué à la His tag.
    Séquence
    Met1-Asn193
    Attributs du produit
    A DNA sequence encoding the Human PUMA/BBC3 (Q9BXH1-1) (1M-193N) was expressed with a polyhistidine tag at the N-terminus.
    Pureté
    >90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product BBC3 Protéine
  • Commentaires

    used as Immunogen for (ABIN6999884, ABIN7234184, ABIN7234185 and ABIN7234186)

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    12 months
  • Antigène
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Autre désignation
    PUMA (BBC3 Produits)
    Synonymes
    BBC3 Protein, Puma Protein, JFY-1 Protein, JFY1 Protein, PUMA Protein, PUMA/JFY1 Protein, BCL2 binding component 3 Protein, Bcl-2 binding component 3 Protein, BBC3 Protein, Bbc3 Protein, bbc3 Protein
    Sujet

    Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.

    Synonym: BBC 3, Bbc3, BBC3_HUMAN, BCL 2 binding component 3, Bcl-2-binding component 3, BCL2 binding component 3, JFY 1, JFY-1, JFY1, p53 up regulated modulator of apoptosis, p53 up-regulated modulator of apoptosis, p53 Upregulated Modulator of Apoptosis, PUMA alpha, PUMA/JFY1

    Poids moléculaire
    20.1 kDa
    Pathways
    Signalisation p53, Positive Regulation of Endopeptidase Activity
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