FGF2 Protein (AA 10-144) (His tag)

N° du produit ABIN7505474

Détail du produit

Antigène: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Type de proteíne: Recombinant

Attributs du protein: AA 10-144

Origine: Rat

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette FGF2 protéine est marqué à la His tag.

Séquence: Pro10-Ala144

Attributs du produit: A DNA sequence encoding the Rat Fgf2 alpha2 (P13109-1) (Pro10-Ala144) was expressed with a polyhistidine tag at the N-terminus.

Pureté: >95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Autre désignation: FGF2 (FGF2 Produits)

Synonymes: BFGF Protein, FGF-2 Protein, FGFB Protein, HBGF-2 Protein, Fgf-2 Protein, Fgfb Protein, bFGF Protein, fibroblast growth factor 2 Protein, fibroblast growth factor 2 (basic) Protein, FGF2 Protein, Fgf2 Protein, fgf2 Protein

Sujet:

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Synonym: Basic fibroblast growth factor,Basic fibroblast growth factor bFGF,BFGF,FGF 2,FGF B,FGF-2,Fgf2,FGF2 basic,FGF2,FGFB,Fibroblast growth factor 2 (basic),Fibroblast growth factor 2,Fibroblast growth factor,basic,HBGF 2,HBGF-2,HBGF2,HBGH 2,HBGH2,Heparin binding growth factor 2 precursor,Heparin-binding growth factor 2,Prostatropin

Poids moléculaire: 15.2 kDa

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins