Bcl-2 Protéine
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- Antigène Voir toutes Bcl-2 (BCL2) Protéines
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Fonction
- Active Recombinant Human Bcl-2 Protein
- Séquence
- AHAGRTGYDN REIVMKYIHY KLSQRGYEWD AGDVGAAPPG AAPAPGIFSS QPGHTPHPAA SRDPVARTSP LQTPAAPGAA AGPALSPVPP VVHLTLRQAG DDFSRRYRRD FAEMSSQLHL TPFTARGRFA TVVEELFRDG VNWGRIVAFF EFGGVMCVES VNREMSPLVD NIALWMTEYL NRHLHTWIQD NGGWDAFVEL YGPSMRPLFD
- Specificité
- Ala2-Asp211
- Pureté
- > 95 % by SDS-PAGE.
- Biological Activity Comment
- Measured by its binding ability in a functional ELISA. Immobilized Human BCL-XL Protein at 2 μg/mL (100 μL/well) can bind BCL2 with a linear range of 3.9-421 ng/mL.
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- Discover our top product BCL2 Protéine
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B-Cell CLL/lymphoma 2 (BCL2) (AA 1-239) protein (GST tag)
BCL2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
B-Cell CLL/lymphoma 2 (BCL2) (AA 5-205) protein (His tag)BCL2 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-211) protein (His-IF2DI Tag)BCL2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
B-Cell CLL/lymphoma 2 (BCL2) (AA 140-239) protein (GST tag)BCL2 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-236) protein (Strep Tag)Crystallography grade BCL2 Origine: Souris Hôte: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
B-Cell CLL/lymphoma 2 (BCL2) (AA 1-239) protein (Strep Tag)Crystallography grade BCL2 Origine: Humain Hôte: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/mL
- Buffer
- Supplied in 20 mM Tris,200 mM NaCl,30 % Glycerol,1 mM DTT, pH 8.0
- Agent conservateur
- Dithiothreitol (DTT)
- Précaution d'utilisation
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -80 °C
- Stockage commentaire
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This product is stable at ≤ -70° C for up to 1 year from the date of receipt.
For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.
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- Antigène
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
- Autre désignation
- Bcl-2 (BCL2 Produits)
- Synonymes
- Bcl-2 Protein, PPP1R50 Protein, bcl-2 Protein, AW986256 Protein, C430015F12Rik Protein, D630044D05Rik Protein, D830018M01Rik Protein, BCL-2 Protein, Bcl2 Protein, BCL2, apoptosis regulator Protein, B cell leukemia/lymphoma 2 Protein, B-cell CLL/lymphoma 2a Protein, B-cell CLL/lymphoma 2 protein Protein, BCL2 Protein, Bcl2 Protein, bcl2a Protein, BCL-2 Protein
- Sujet
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Description: This protein is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
Name: BCL2, Bcl-2, PPP1R50, apoptosis regulator Bcl-2,Bcl-2,PPP1R50
- ID gène
- 596
- UniProt
- P10415
- Pathways
- Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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