TNF alpha Protéine
Aperçu rapide pour TNF alpha Protéine (ABIN7937246)
Antigène
Voir toutes TNF alpha ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Fonction
- Recombinant Rat Tumor Necrosis Factor-alpha/TNFSF2
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Séquence
- LRSSSQNSSD KPVAHVVANH QAEEQLEWLS QRANALLANG MDLKDNQLVV PADGLYLIYS QVLFKGQGCP DYVLLTHTVS RFAISYQEKV SLLSAIKSPC PKDTPEGAEL KPWYEPMYLG GVFQLEKGDL LSAEVNLPKY LDITESGQVY FGVIAL
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Less than 1 EU/ug of rRtTNF-alpha as determined by LAL method.
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Biological Activity Comment
- Fully biologically active when compared to standard. The ED50 as determined by a cytotoxicity assay using murine L929 cells is less than 0.05 ng/ml, corresponding to a specific activity of > 2.0 x107 IU/mg in the presence of actinomycin D.
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Commentaires
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Approximately 17.2 kDa, a single non-glycosylated polypeptide chain containing 156 amino acids.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- Lyophilized from a 0.2 um filtered concentrated solution in 20 mM PB, pH 7.2, 150 mM NaCl.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
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Date de péremption
- 12 months
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- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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Autre désignation
- Tumor Necrosis Factor-alpha
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Poids moléculaire
- 17.2 kDa
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ID gène
- 24835
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UniProt
- P16599
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Pathways
- Signalisation NF-kappaB, Apoptose, Caspase Cascade in Apoptosis, Signalisation TLR, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
Antigène
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