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IL-4 Protéine

IL4 Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 96 % by SDS-PAGE and HPLC analyses. Active
N° du produit ABIN871822
  • Antigène Voir toutes IL-4 (IL4) Protéines
    IL-4 (IL4) (Interleukin 4 (IL4))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 31
    • 14
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Source
    • 39
    • 20
    • 15
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Séquence
    MHIHGCDKNH LREIIGILNE VTGEGTPCTE MDVPNVLTAT KNTTESELVC RASKVLRIFY LKHGKTPCLK KNSSVLMELQ RLFRAFRCLD SSISCTMNES KSTSLKDFLE SLKSIMQMDYS
    Pureté
    > 96 % by SDS-PAGE and HPLC analyses.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 1EU/µg of rmIL-4 as determined by LAL method.
    Top Product
    Discover our top product IL4 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in 10mM HAc to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.
    Stock
    4 °C/-20 °C
  • Antigène
    IL-4 (IL4) (Interleukin 4 (IL4))
    Autre désignation
    IL-4 (IL4 Produits)
    Synonymes
    IL4 Protein, IL-4 Protein, BCGF-1 Protein, BCGF1 Protein, BSF-1 Protein, BSF1 Protein, Il-4 Protein, Il4e12 Protein, IL2 Protein, interleukin 4 Protein, IL4 Protein, Il4 Protein
    Sujet
    Interleukin-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy.
    Pathways
    Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation
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