CCL5 Protéine

N° du produit ABIN988214

Détail du produit

Antigène: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Activité biologique: Active

Origine: Humain

Source: Escherichia coli (E. coli)

Séquence: SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEM

Attributs du produit: Fully biologically active when compared to standard. The ED50 determined by a chemotaxis bioassay using human monocytes is less than 30 ng/ml, corresponding to a specific activity of >, 3.3 × 104 IU/mg.

Pureté: > 98 % by SDS-PAGE and HPLC analyses.

niveau d'endotoxine: Level Less than 1EU/µg of rHuRANTES/ CCL5 as determined by LAL method

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

Stock: 4 °C

Détail du antigène

Antigène: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Autre désignation: RANTES/ CCL5 (CCL5 Produits)

Synonymes: Rantes Protein, Scya5 Protein, D17S136E Protein, RANTES Protein, SCYA5 Protein, SIS-delta Protein, SISd Protein, TCP228 Protein, eoCP Protein, MuRantes Protein, C-C motif chemokine 5-like Protein, C-C motif chemokine ligand 5 Protein, chemokine (C-C motif) ligand 5 Protein, LOC100230935 Protein, CCL5 Protein, Ccl5 Protein

Sujet: CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells. Synonym: RANTES/ CCL5, Human. Formulation: Lyophilized from a 0.2µm filtered concentrated solution in 20mM PB, pH 7.4, 100mM NaCl.

Poids moléculaire: 7.8 kDa, a single non-glycosylated polypeptide chain containing 68 amino acids.

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration